RO purified water equipment

Technical features

★ The system adopts full automatic control (manual control is also possible), and the automatic backwash and regeneration programs can be set when the system is running;

★ The first-stage reverse osmosis and second-stage reverse osmosis are equipped with return pipes, and the reverse osmosis equipment is equipped with chemical cleaning devices and disinfection devices;

★ A pH adjustment device is installed between the primary reverse osmosis and the secondary reverse osmosis to ensure that the conductivity of the water produced by the equipment meets the requirements of the pharmacopoeia;

★ The secondary reverse osmosis membrane uses a positively charged anti-pollution reverse osmosis membrane to ensure that the reverse osmosis equipment can operate stably for a long time

★ The first-stage reverse osmosis pipeline is made of 304 stainless steel, and the second-stage reverse osmosis pipeline is made of 316L stainless steel:

★ Online conductivity detection instruments are installed in the first-stage reverse osmosis and second-stage reverse osmosis equipment, and the conductivity of the produced water can be viewed at any time;

★ There is a low-pressure protection switch before the first-stage reverse osmosis, and a low-pressure protection and high-pressure protection switch before the second-stage reverse osmosis

★ The recovery rate of primary and secondary reverse osmosis water can be adjusted, the recovery rate of primary reverse osmosis is 60%-65%, and the recovery rate of secondary reverse osmosis is 70%;

★ The purified water storage tank is equipped with a breathing filter, and the delivery pipeline is equipped with an ultraviolet sterilizer and a microporous filter to ensure that the purified water meets the hygiene requirements.

Features

★ Online water quality detection function to understand the water quality at any time;

★ Fully automatic control by programmable controller, humanized operation display system, the equipment can be operated with just one button, and it is equipped with water cut-off protection and full water shutdown function;

★ The system automatically flushes when it is turned on, avoiding the trouble of manual flushing, so as to effectively extend the service life of the RO reverse osmosis membrane;

★ Beautiful and exquisite appearance, safe insulation performance meets GLP safety requirements

★ Real-time display of flushing, water making, water fullness, water shortage and maintenance status, and with sound and light alarm function;

★ Modular and quick-connect design, easy to install and maintain, small footprint, more convenient to maintain;

★ The RO membrane equipment has a timed automatic flushing program when it is turned on, and has functions such as power-on self-check, water shortage protection alarm, power failure automatic reset, low pressure and high pressure protection, etc.

Equipment Features

1. The structural design should be simple, reliable, and easy to assemble and disassemble.

2. To facilitate disassembly, replacement and cleaning of parts, the design of the actuator should use standardized, universal and systematic parts as much as possible.

3. The inner and outer wall surfaces of the equipment should be smooth and flat, without dead corners, easy to clean and sterilize. The surface of the parts should be chrome-plated to resist corrosion and prevent rust. Avoid using paint on the outside of the equipment to prevent peeling.

4. Equipment for preparing purified water should be made of low-carbon stainless steel or other materials that have been proven not to pollute water quality. Equipment for preparing purified water should be cleaned regularly and the cleaning effect should be verified.

5. Materials that come into contact with water for injection must be high-quality low-carbon stainless steel or other materials that have been proven not to pollute the water quality. Equipment for preparing water for injection should be cleaned regularly and the cleaning effect should be verified.

6. The storage period of purified water should not exceed 24 hours. Its storage tank should be made of stainless steel or other materials that are proven to be non-toxic, corrosion-resistant, and do not leak polluting ions. To protect its vent, a hydrophobic sterilizing filter that does not shed fibers should be installed. The inner wall of the storage tank should be smooth, and there should be no dead corners or sand holes in the pipes and welds. Sensors that display parameters such as liquid level, temperature, pressure, etc. that will not cause stagnant water pollution should be used. The storage should be cleaned, disinfected and sterilized regularly, and the cleaning and sterilization effects should be verified.

7. Transportation of pharmaceutical water

(1) Purified water and pharmaceutical water should be delivered by stainless steel pumps that are easy to disassemble, clean and disinfect. In situations where purified water and water for injection need to be delivered by compressed air or nitrogen, the compressed air and nitrogen must be purified.

(2) Purified water should be transported by circulating pipelines. The pipeline design should be simple and avoid blind pipes and dead corners. Pipes should be made of stainless steel pipes or other pipes that have been verified to be non-toxic, corrosion-resistant, and non-leaking polluting ions. Valves should be sanitary valves without dead corners, and the flow direction of purified water should be marked.

(3) Pipes and pumps used to transport purified water and water for injection should be cleaned, disinfected and sterilized regularly and can only be put into use after verification and approval.

8. The design of pressure vessels must be undertaken by licensed units and qualified personnel and must be carried out in accordance with the relevant provisions of the National Standard of the People's Republic of China "Steel Pressure Vessels" (GB150-80) and the "Regulations on Safety Technical Supervision of Pressure Vessels".

Process

1. Pretreatment + two-stage reverse osmosis

2. Pretreatment + single-stage reverse osmosis + electrodeionization

3. Pretreatment + two-stage reverse osmosis + electrodeionization + multi-effect distillation + sterilization distribution system

Reference standards for pharmaceutical purified water equipment

Chinese Pharmacopoeia GMP 2020 Edition Purified Water Standard, EU and FDA GMP Specifications and Implementation Guidelines, Pharmaceutical Purified Water Preparation Equipment JB/T20194-2019, Pharmaceutical Process Water System Design Specification GB50913-2013.

The system is automatically controlled, and the operation is simple and convenient to manage. The equipment has the advantages of intelligent automatic controller, simple and convenient operation, stable water quality, low operating cost, green environmental protection, and easy maintenance.

Application Areas

Biological preparations, in vitro diagnostic reagents, medical devices, pharmaceutical industry, health products, oral liquids, cosmetics, food, medical infusions, pharmaceutical preparations, genetic engineering, water for kidney dialysis, disinfectants, eye drops, non-woven fabrics industry, medical supplies (gauze, oral devices, wet wipes, protective clothing, medical gloves, drainage tubes, etc.)